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银屑病是一种非感染性的慢性炎症疾病,其病理改变主要为表皮细胞分裂加快,病程往往在数年至数十年之久,反复发作,在治疗方面是比较困难的。自70年代起世界各国学者应用UVA结合口服或外涂补骨脂素,特别是8—甲氧补骨脂素(8—MOP)治疗银屑病取得一定的成效。Parish等自1974年首次报告用口服8—MOP的光敏照射治疗银屑病以来,到1980年上半年仅在美国就已治疗了几千名患者,认为谨慎掌握剂量,近期危险性极小,疗效是肯定的。我们应用这一新的疗法治疗了部分皮肤疾病,现将40例银屑病(其中付银屑病1例暂列其中)的近期疗效总结如下。
Psoriasis is a non-infectious chronic inflammatory disease, the pathological changes are mainly epidermal cell division to speed up, the course of the disease often in the years to decades, repeated attacks, the treatment is more difficult. Since the 1970s, scholars from all over the world have achieved some success by applying UVA combined with oral or external application of psoralen, especially 8-methoxy psoralen (8-MOP) in the treatment of psoriasis. Parish et al. Have reported thousands of patients in the United States alone in the first half of 1980, treating lightly irradiated oral 8-MOP for psoriasis for the first time since 1974, believing that caution should be given to dosage, with minimal immediate risk and efficacy Yes We have applied this new treatment to treat some skin diseases. We have summarized the short-term effects of 40 cases of psoriasis, of which 1 case of psoriasis was temporarily listed.