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目的对比分析腹腔镜手术联合甲氨蝶呤(MTX)治疗与中药联合MTX保守治疗异位妊娠的临床效果。方法将100例异位妊娠患者随机分为腹腔镜+MTX组和中药+MTX组,各50例。腹腔镜+MTX组采用腹腔镜联合MTX治疗,中药+MTX组采用口服中药异位妊娠方加味联合MTX。观察并比较两组患者的术中状况和治疗效果。结果腹腔镜+MTX组的住院天数和出院时的血人绒毛膜促性腺激素(β-HCG)明显低于中药+MTX组,而住院费用明显高于中药+MTX组,差异均有统计学意义(P<0.05)。腹腔镜+MTX组总有效率为88%,中药+MTX组总有效率为68%,两组疗效比较,差异有统计学意义(P<0.05)。结论与中药联合MTX治疗异位妊娠相比,腹腔镜联合MTX治疗方法具有住院时间短、疗效好等优点,是年轻且有生育意愿患者的最佳治疗方法,值得推广。
Objective To compare the clinical effects of laparoscopic surgery combined with methotrexate (MTX) with traditional Chinese medicine (MTX) and conservative treatment of ectopic pregnancy. Methods 100 cases of ectopic pregnancy were randomly divided into laparoscopic + MTX group and traditional Chinese medicine + MTX group, 50 cases each. Laparoscopy + MTX group was treated with laparoscopy combined with MTX. Traditional Chinese medicine + MTX group was treated with oral traditional Chinese medicine ectopic pregnancy plus MTX. Observed and compared the two groups of patients with intraoperative status and treatment. Results The hospitalization days and the serum levels of human chorionic gonadotropin (β-HCG) in laparoscopic + MTX group were significantly lower than those in traditional Chinese medicine + MTX group, while the cost of hospitalization was significantly higher than that in traditional Chinese medicine + MTX group (P <0.05). The total effective rate was 88% in laparoscopic + MTX group and 68% in traditional Chinese medicine plus MTX group. The difference was statistically significant (P <0.05). Conclusions Compared with traditional Chinese medicine combined with MTX in the treatment of ectopic pregnancy, laparoscopic combined with MTX has the advantages of short hospital stay and good curative effect. It is worthy of promotion because it is the best treatment for young and pregnant patients.