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[目的]探讨颅脑损伤后抑郁的发生情况以及与影响抑郁发生的相关因素。[方法]收集2006年1月~2011年1月在我院住院治疗的脑外伤患者共计240名,病案科收集患者的基本人口学资料,并采用自制问卷收集抑郁发生的相关因素。采用卡方检验和Logistic回归分析影响抑郁的因素。[结果]抑郁在颅脑损伤病人中的发生率为47.00%。脑外伤患者抑郁组与非抑郁组两组在年龄、文化程度、出院后是否恢复工作、是否有经济赔偿、两组患者入院时意识得分(CGS)、两组患者生命质量的躯体健康(PCS)和精神健康得分(MCS)差异均有统计学意义。采用Logistic回归发现,患者文化程度为大专以上、入院时的意识得分(CGS)﹥8分、PCS﹤55分和MCS﹤57分能显著影响患者患抑郁的风险,OR值(95%CI)为0.51(0.33~0.98),0.47(0.22~0.74),3.56(2.53~7.94)和4.13(1.96~7.45)。[结论]因此,颅脑外伤患者患抑郁症风险较高,并且与受伤时意识情况、患者文化程度和患者生命质量有密切联系。
[Objective] To investigate the incidence of depression after craniocerebral injury and related factors that affect the occurrence of depression. [Methods] A total of 240 traumatic brain trauma patients hospitalized in our hospital from January 2006 to January 2011 were collected. The basic demographic data of patients were collected by the case record department and the related factors of depression were collected by self-made questionnaire. Factors affecting depression were analyzed using chi-square test and Logistic regression. [Results] The incidence of depression in patients with craniocerebral injury was 47.00%. The patients with traumatic brain injury in depression group and non-depression group were divided into two groups according to their age, education level, whether to resume their work after discharge, whether there is financial compensation, consciousness score (CGS) at hospital admission, physical fitness (PCS) And mental health score (MCS) were statistically significant differences. The results of Logistic regression showed that the patients had a college education or above, with CGS> 8 on admission, and PCS <55 and MCS <57 significantly affected the risk of depression in patients with OR (95% CI) 0.51 (0.33-0.98), 0.47 (0.22-0.74), 3.56 (2.53-7.94) and 4.13 (1.96-7.45). [Conclusion] Therefore, the patients with craniocerebral injury have a higher risk of depression and are closely related to the consciousness, patient’s education level and patient’s life quality when they are injured.