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甲胎蛋白(AFP)是由胚胎的卵黄囊合成,而后是由未成熟的胎儿肝细胞合成,它的最高合成速度是在10—20周的胎儿。合成的速度,是随着胎儿肝细胞的逐渐成熟而渐渐下降的,妊娠期胎儿心血AFP浓度的波动,在血及羊水内也都有所反映。羊水内血AFP系来自胎儿尿,小部分则来自胎儿的胃肠道及羊膜与绒毛膜分泌。目前甲胎蛋白抗的清的制备取自人工流产4—6个月胎儿心血,分离出血清作为抗原,免疫马匹或家兔制备抗血清,由于胎
Alpha-fetoprotein (AFP) is synthesized from the yolk sac of an embryo and then synthesized from immature fetal hepatocytes, with the highest rate of synthesis being in the fetus at 10-20 weeks. The rate of synthesis is gradually decreased with the gradual maturation of fetal hepatocytes. The fluctuations in the concentration of fetal AFP during pregnancy are also reflected in the blood and amniotic fluid. AFP derived from amniotic fluid from fetal urine, a small part of the fetus from the gastrointestinal tract and amniotic membrane and chorion secretion. At present, the preparation of anti-fetoprotein anti-Qing taken from abortion 4-6 months fetal heart blood, serum was isolated as an antigen, immune horses or rabbits to prepare antiserum, due to fetal