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3种结构类型不同的增溶剂对维生素D_2的增溶效应,聚氧乙烯蓖麻油类大于聚氧乙烯脱水山梨醇脂肪酸酯类及聚氧乙烯脂肪醇醚类。在聚氧乙烯蓖麻油类C-125中维生素D_2的稳定性亦大于其余的两种增溶剂。 在吐瘟80胶团中丁基羟基茴香醚主要位于胶团的栅层深部,由于可与维生素D_2处于胶团的相同部位,故较位于栅层浅部及水相之中的没食子酸丙酯,有效地延缓了维生素D_2的自动氧化作用。
The solubilization effect of three kinds of solubilizers with different structure types on vitamin D 2 was higher than polyoxyethylene sorbitan fatty acid esters and polyoxyethylene fatty alcohol ethers. The stability of vitamin D 2 in polyoxyethylene castor oil C-125 is also greater than that of the other two solubilizers. Butylated hydroxy anisole in the micelles of Vomiting 80 is mainly located in the deep part of the grid layer of micelles. Compared with vitamin D_2 in the same part of the micelle, the content of propyl gallate is higher in the shallow part of the grid and in the aqueous phase , Effectively delayed the auto-oxidation of vitamin D 2.