Dynamic changes in cerebral microcirculation and hypoxia in the early stages of diffuse axonal injur

• 作 者: Jinning Song Xiaobin Liu Jingy
• 机 构: DepartmentofNeurosurgery,DepartmentofNuclearMedicine
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2011年20期
• 关键词: 神经元损伤 大脑皮质 早期阶段 动态变化 脑缺氧 弥漫性 轴 微循环障碍 diffuse axonal injury microcirculation hy
• 基金项目: Supported by： the National Natural Science Foundation of China, No. 30471774＊, the Program for New Century Excellent Talents in University, Ministry of Education, China, No. NCET-05-0831＊

This study demonstrated that damage to the cerebral microvasculature,the formation of microthrombi and swelling of vascular endothelial cells occur early and peak 12 hours after injury in a rat model of diffuse axonal injury.Moreover,these pathological ch