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目的:对免疫比浊法(ITA)和乳胶凝集法(LAT)检测类风湿因子(RF)结果做比较分析。方法:70例类风湿关节炎(RA)和非类风湿关节炎(non~RA)的风湿病患者同时采用ITA和LAT法检测血清RF水平。结果:45例RA中LAT阳性率为68.9%,而ITA阳性率为86.7%,明显高于乳胶法,两者比较有显著性差异(P<0.05)。LAT检测阳性的RF滴度与同组ITA法RF定量结果呈平行性关系,二者相关系数r=0.712,有显著相关性(P<0.001)。结论:ITA和LAT检测RF具有一致性,但ITA优于LAT。
Objective: To compare and analyze the results of rheumatoid factor (RF) detected by immuno turbidimetry (ITA) and latex agglutination (LAT). Methods: Serum RF levels were measured by ITA and LAT in 70 rheumatoid arthritis (RA) and non-rheumatoid arthritis (RA) patients. Results: The positive rate of LAT in 45 cases of RA was 68.9%, while the positive rate of ITA was 86.7%, which was significantly higher than that of latex method (P <0.05). There was a significant correlation between the RF titer of positive LAT test and RF quantitative test of ITA in the same group (r = 0.712, P <0.001). Conclusion: ITA and LAT detection of RF consistency, but ITA better than LAT.