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60年代以来利多卡因逐步广泛用于临床,现已成为治疗和预防室性心律失常的重要药物。但是若应用不当,也有诱发心脏停搏的危险,应引起重视,现报告5例如下: 例1:男,68岁。典型心绞痛病史六年余,近几年来发作变频,疼痛程度加重,持续时间延长。1982年12月29日晨突然发生胸骨后撕裂样剧痛,大汗淋漓,口含硝酸甘油不缓解,下午一时心电图示Ⅱ、Ⅲ、avF呈QS形,ST段上抬,Tv_1-v_3高尖,STv_4-v_6水平下移,记录心电图过程中有短时间(约1分钟)的完全性房室脱离,P88/分,R58/分,呈交界区逸搏性心律,迅速恢复房室传导,P—R正常,诊断急性下壁心肌梗塞,阵发性Ⅲ°A—VB。因有室早静注
Since the 1960s, lidocaine has gradually been used clinically and has become an important drug for the treatment and prevention of ventricular arrhythmias. However, if improper application, there is also the risk of cardiac arrest, should pay attention to the report of 5 cases are as follows: Example 1: Male, 68 years old. A history of typical angina more than six years, episodes of frequency in recent years, the pain increased, the duration extended. On the morning of December 29, 1982, a sudden sternum tear occurred after a sharp pain and sweating. No nitroglycerin was contained in the mouth. The electroencephalogram at 11 o’clock in the afternoon showed QS shape, ST elevation and Tv_1-v_3 high Sharp, STv_4-v_6 level down, the recording process of ECG a short time (about 1 minute) complete atrioventricular detachment, P88 / min, R58 / min, border junction escape stroke rhythm, rapid recovery of atrioventricular conduction, P-R normal, diagnosis of acute inferior myocardial infarction, paroxysmal Ⅲ ° A-VB. Because of room early intravenous injection