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目的观察中西医结合治疗单纯型糖尿病视网膜病变临床疗效。方法将166例单纯型糖尿病视网膜病变患者随机分为2组,治疗组106例(212眼)予滋阴补肾中药口服联合卡波金吸入治疗,对照组60例(120眼)予以滋阴补肾中药口服治疗,2组均1个月为1个疗程,间隔10 d后进行下1个疗程,2个疗程后统计临床疗效,并进行血液流变学检测及血气分析。结果 2组总有效率比较差异有统计学意义(P<0.01),治疗组疗效优于对照组。治疗组治疗后全血黏度(高切)、全血黏度(低切)、血浆黏度、红细胞沉降率及p H值均较本组治疗前明显降低(P<0.01,P<0.05),氧分压升高(P<0.01),且全血黏度(高切)、全血黏度(低切)、血浆黏度、氧分压及p H值改善优于对照组(P<0.05)。结论滋阴补肾中药联合卡波金吸入治疗单纯型糖尿病视网膜病变,能明显改善血液流变学指标及血气分析指标,疗效优于单纯滋阳补肾中药治疗。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of simple diabetic retinopathy. Methods One hundred and sixty-six patients with simple diabetic retinopathy were randomly divided into two groups: 106 cases (212 eyes) treated by Ziyin Bushen Chinese medicine combined with Kapokin inhalation, and 60 cases (120 eyes) Oral treatment, two groups were 1 month for a course of treatment, an interval of 10 d after a course of treatment, after 2 courses of statistical clinical efficacy, and hemorheological tests and blood gas analysis. Results The total effective rate of the two groups was statistically significant difference (P <0.01), the treatment group than the control group. After treatment, the whole blood viscosity (high shear), whole blood viscosity (low shear), plasma viscosity, erythrocyte sedimentation rate and p H value of the treatment group were significantly lower than those before treatment (P <0.01, P < (P <0.01), and the whole blood viscosity (high shear), whole blood viscosity (low shear), plasma viscosity, oxygen partial pressure and p H value improved better than the control group (P <0.05). Conclusion Ziyin Bushen Chinese medicine combined with Kapokin inhalation treatment of simple diabetic retinopathy can significantly improve the index of hemorheology and blood gas analysis, the curative effect is better than that of traditional Chinese medicine of nourishing kidney and invigorating the kidney.