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目的:观察柴胡疏肝散联合恩替卡韦治疗慢性乙型肝炎的临床治疗效果。方法:选取我院2015年12月至2017年2月确诊的慢性乙型肝炎患者128例,随机分为实验组和对照组两组,实验组用柴胡疏肝散加减联合恩替卡韦治疗,而对照组仅用恩替卡韦治疗,比较两组患者的临床治疗效果,E抗原转阴率及谷丙转氨酶复常率。结果:实验组的有效率显著高于对照组,具有差异显著性(P<0.05);E抗原转阴率及谷丙转氨酶复常率也均显著高于对照组,具有差异显著性(P<0.05)。结论:柴胡疏肝散加减联合恩替卡韦治疗慢性乙型肝炎临床效果显著,提高了乙肝E抗原转阴率及谷丙转氨酶复常率,具有较高的临床应用价值。
Objective: To observe the clinical efficacy of Chaihu Shugan San combined with entecavir in the treatment of chronic hepatitis B. Methods: A total of 128 chronic hepatitis B patients diagnosed in our hospital from December 2015 to February 2017 were randomly divided into experimental group and control group. The experimental group was treated with Chaihu Shugan Powder combined with entecavir, The control group only treated with entecavir, the clinical efficacy of two groups were compared, E antigen negative rate and alanine aminotransferase normalization rate. Results: The effective rate of the experimental group was significantly higher than that of the control group (P <0.05), and the negative rate of E antigen and the normal rate of alanine aminotransferase were also significantly higher than those of the control group (P < 0.05). Conclusion: Chaihu Shugan Powder combined with entecavir in the treatment of chronic hepatitis B has significant clinical effect, increased hepatitis B E antigen negative rate and alanine aminotransferase normalization rate, and has high clinical value.