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目的探讨四磨汤联合小剂量红霉素治疗早产儿喂养不耐受的临床效果。方法选取喂养不耐受的早产儿98例,按用药不同分为四磨汤组30例,小剂量红霉素组30例,两药联合治疗组38例。比较3组患儿呕吐、腹胀、胃储留等症状持续时间。结果联合治疗组患儿呕吐、腹胀、胃储留等症状改善时间早于另2组,临床治疗显效率和总有效率均高于对照组,差异有统计学意义(P<0.05或P<0.01)。结论四磨汤联合小剂量红霉素治疗早产儿喂养不耐受疗效确切,安全可靠,值得临床推广。
Objective To investigate the clinical effect of Sihuang Decoction combined with low dose erythromycin in the treatment of premature infant feeding intolerance. Methods 98 cases of premature infants who were intolerant to feeding were selected and divided into four groups according to different drugs: 30 cases in the SJT group, 30 cases in the low dose erythromycin group and 38 cases in the combination of the two drugs. The duration of symptoms such as vomiting, abdominal distension and gastric retention were compared between the three groups. Results The improvement of vomiting, abdominal distension, gastric retention and other symptoms in the combined treatment group was earlier than that in the other two groups. The effective rate and total effective rate of clinical treatment in the combined treatment group were significantly higher than those in the control group (P <0.05 or P <0.01) ). Conclusion Four mill soup combined with low-dose erythromycin in treating preterm infants with intolerance is effective, safe and reliable, and worthy of clinical promotion.