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目的:了解深圳市宝安区2008~2011年围产儿出生缺陷发生状况及其影响因素,以便制定有效的干预对策,降低出生缺陷发生率,为提高出生人口素质提供可靠依据。方法:对2008~2011年在深圳市宝安区人民医院接受产前检查或住院分娩的孕满28周至产后7天内的13 733例围产儿进行出生缺陷及相关因素监测分析。结果:14年围产儿出生缺陷儿798例,检出率581.08/万,各年度差异无统计学意义(P>0.05)。2男性出生缺陷率明显高于女性。母亲孕龄≥35岁的出生缺陷明显高于其他组。3前5位出生缺陷类型分别为先天性心脏病,G-6PD缺乏症,多指(趾),唇裂合并腭裂,马蹄内翻足。前4种类型均高于全国平均水平。42008~2011年围产儿死亡为143例,其中出生缺陷死亡占70.63%。结论:政府给予配套经费,落实出生缺陷综合防治措施。发挥社康中心妇幼保健网底作用,实现社区-社康中心-医院婚前、孕前、孕期、分娩期的系统保健管理工作。
Objective: To understand the occurrence and its influencing factors of birth defects in perinatals from 2008 to 2011 in Bao’an District, Shenzhen in order to make effective intervention measures to reduce the incidence of birth defects and provide a reliable basis for improving the quality of birth population. Methods: A total of 13 733 perinatal infants undergoing prenatal examination or hospital delivery from 28 weeks pregnant to 7 days postpartum were enrolled in 2008 ~ 2011 in Bao’an District People’s Hospital of Shenzhen City for monitoring of birth defects and related factors. Results: There were 798 infants with birth defects in 14 years, the detection rate was 581.08 / million, there was no significant difference in each year (P> 0.05). 2 male birth defects were significantly higher than women. Mother gestational age ≥35 years old birth defects were significantly higher than other groups. 3 The top 5 birth defects were congenital heart disease, G-6PD deficiency, multiple fingers, cleft lip with cleft palate, and clubfoot. The first four types are higher than the national average. 42008 ~ 2011 perinatal death was 143 cases, of which birth defects accounted for 70.63%. Conclusion: The government will provide supporting funds to implement comprehensive prevention and control measures for birth defects. Give full play to the role of maternal and child health care centers in community health centers and achieve community health management in community-community health centers-hospitals before marriage, pregnancy, pregnancy and childbirth.