论文部分内容阅读
目的：观察机体受损伤后的不同时间内，白细胞吞噬功能和血浆中丙二醛（ＭＤＡ）含量的变化。方法：分别于家兔颌骨粉碎性骨折致伤前、伤后６ｈ和１２ｈ抽血，测定全血化学发光强度和血浆ＭＤＡ含量。结果：伤后化学发光的出峰时间提前，与伤前组比较Ｐ＜０．０５；伤后各组的全血化学发光强度明显大于伤前组（Ｐ＜０．０５）；血浆ＭＤＡ含量，伤后各组都升高（Ｐ＜０．０１）。结论：机体受损伤之后白细胞吞噬氧化活性增强，对组织细胞的脂质过氧化加剧，造成血浆ＭＤＡ含量升高
Objective: To observe the phagocytosis of leucocytes and the content of malondialdehyde (MDA) in plasma at different time after injury. Methods: Blood samples were collected at 6 h and 12 h after traumatic comminuted fractures in rabbits, respectively. The chemiluminescence intensity and the content of MDA in plasma were measured. Results: The peak time of chemiluminescence after injury was earlier than that of the pre-injury group (P <0.05). The chemiluminescence intensity of whole blood in each group was significantly higher than that of the pre-injury group (P <0.05) All groups were increased after injury (P <0.01). CONCLUSION: The leukocyte phagocytic oxidative activity is enhanced after the body is damaged, and the lipid peroxidation of tissue cells is aggravated, resulting in the increase of plasma MDA content