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目的:探讨甲氨蝶呤与米非司酮联合应用治疗异位妊娠的临床疗效。方法:选取我院2011年1月至2016年1月收治的30例异位妊娠患者为研究对象,所有患者均符合保守治疗条件,采用甲氨蝶呤联合米非司酮治疗,观察临床治疗效果及治疗前后血β-HCG水平、孕酮水平以及包块直径的变化。结果:治疗2周后,入组的30例患者中显效11例,有效14例,无效5例,治疗总有效率为83.33%(25/30)。用药后患者血β-HCG水平、孕酮水平以及包块直径显著低于用药前,前后比较差异有统计学意义(P<0.05)。结论:甲氨蝶呤与米非司酮联合应用治疗异位妊娠临床疗效显著,具有一定的临床应用价值。
Objective: To investigate the clinical efficacy of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods: Thirty cases of ectopic pregnancy treated in our hospital from January 2011 to January 2016 were selected as the research objects. All patients were treated with methotrexate combined with mifepristone, and the clinical effects were observed And before and after treatment, blood β-HCG levels, progesterone levels, and changes in the diameter of the mass. Results: After 2 weeks of treatment, 11 patients were markedly effective in 30 patients, 14 were effective and 5 were ineffective. The total effective rate was 83.33% (25/30). The levels of β-HCG, progesterone and mass of the patients’ blood after treatment were significantly lower than those before and after treatment (P <0.05). Conclusion: The combination of methotrexate and mifepristone in the treatment of ectopic pregnancy has significant clinical efficacy, and has certain clinical value.