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目的分析38例(43例次)腹膜透析相关肠源性腹膜炎的病原菌及药敏。方法回顾性分析43例次肠源性腹膜炎患者的临床资料。结果病原菌为革兰阴性杆菌38例次,肠球菌6例次,两种菌混合感染5例次。最常见病原菌为革兰阴性杆菌,以大肠杆菌及肺炎克雷伯杆菌为主。革兰阴性杆菌对头孢哌酮舒巴坦、亚胺培南及美罗培南敏感。肠球菌对氨苄西林、万古霉素、替考拉宁和利奈唑胺敏感。因肠源性腹膜炎而致拔管1例、转血液透析1例、死亡4例,病原菌均为革兰阴性杆菌。肠球菌致病患者均得到完全缓解。结论腹膜透析患者肠源性腹膜炎最常见病原菌为革兰阴性菌,应选择敏感药物治疗。
Objective To analyze the pathogens and drug sensitivity of 38 cases (43 cases) of peritoneal dialysis related intestinal peritonitis. Methods The clinical data of 43 patients with enterocolitis peritonitis were retrospectively analyzed. Results The pathogenic bacteria were gram negative bacilli 38 times, enterococci 6 times, mixed infection of the two bacteria 5 times. The most common pathogens are Gram-negative bacilli, Escherichia coli and Klebsiella pneumoniae-based. Gram-negative bacilli are sensitive to cefoperazone sulbactam, imipenem and meropenem. Enterococcus is sensitive to ampicillin, vancomycin, teicoplanin and linezolid. One case of extubation due to enterogenous peritonitis, one case of hemodialysis hemodialysis, and four deaths. The pathogenic bacteria were all Gram-negative bacilli. Enterococci cause patients have been completely relieved. Conclusion Peritoneal dialysis patients with enterocolitis peritonitis is the most common pathogen of gram-negative bacteria, should choose a sensitive drug treatment.