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本研究采用中华儿科学会(1982)关于缺铁性贫血(IDA)的实验室诊断指标为Hb<110g/L,FEP>500μg/L,SF<16mg/L,通过补铁3个月后,Hb升高10g/L。以上4项中任选3项。同时对IDA患儿的智力(IQ)发育,免疫功能及做功能力进行测定。然后把IDA患儿分成3组,第一组补铁加维生素C连续80~90天,第二组为食用安慰剂组,第三组为不贫血正常对照组。3个月后重复测定上述指标。结果证明6~36个月婴儿患有IDA占30.5%,智能发育商DQ值(Gesell法),IDA患儿为95,3±9.7,正常儿为101,6±10.3(P<0.01);4~6.5岁幼儿中IDA患病率为36.8%,测得IQ值(Wppsi法)包括语言IQ,操作IQ,总IQ值均低于正常儿,补铁3个月后,DQ值与IQ值均有上升,前后有显著性差异,与正常对照组比较无明显差异,说明已恢复正常。IDA对4~7岁幼儿做功能力PWC170补铁前为172.4±25.3,补铁后为198.5±44.6,补铁后有显著提高。IDA小儿免疫功能下降(PHA刺激淋转为93308±50403cpm/瓶),补铁后为130425±34445cpm/瓶;粪便S-?
In our study, the laboratory diagnostic indexes of iron deficiency anemia (IDA) in China Pediatric Society (1982) were Hb <110g / L, FEP> 500μg / L and SF <16mg / L. Increase 10g / L. Any of the above four options 3. At the same time, the IQ (IQ) development, immune function and work ability of IDA children were determined. Then the IDA children were divided into three groups, the first group of iron supplementation with vitamin C for 80 to 90 days, the second group for the placebo group, the third group is not anemia normal control group. 3 months after repeated determination of the above indicators. The results showed that 6 to 36 months of infants with IDA accounted for 30.5%, DQ value of intelligent development (Gesell method), IDA children was 95,3 ± 9.7, normal children was 101,6 ± 10.3 ( P <0.01). The prevalence of IDA among children aged 4 ~ 6.5 years was 36.8%. The measured Wppsi method included language IQ, manipulative IQ and total IQ values were lower than normal Iron 3 months later, DQ value and IQ values have increased, before and after significant differences, compared with the normal control group no significant difference, that has returned to normal. IDA of 4 to 7-year-old children doing power PWC170 172.4 ± 25.3 before iron supplementation, 198.5 ± 44.6 after iron supplementation, significantly increased after iron supplementation. IDA decreased immune function in children (PHA stimulation leaching to 93,308 ± 50,403 cpm / bottle), after iron supplementation for the 130,425 ± 34,445 cpm / bottle;