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先天性的人巨细胞病毒(HCMV)感染是引起出生缺陷和胎儿致死性疾病的一个重要原因,而且到目前尚无有效的治疗方法。对先天性的 HCMV 感染的研究国内外大多数学者用新生儿尿样和脐带血为材料,其感染率在1～2％左右。这一结果对在孕早期宫内疾病做出诊断帮助不大。为此,研究一种在孕早期对先天性HCMV 感染的产前诊断方法是十分必要的,对预防带有疾病的胎儿出生有重要的意义。我们在国内首次利用聚合酶链反应(PCR)技术对68例早孕人胚组织进行了 HCMV 感染的研究,检测结果显示在16例绒毛样品中有特异性 HCMV 的基因
Congenital human cytomegalovirus (HCMV) infection is a cause of birth defects and fetal fatal disease, an important reason, and so far there is no effective treatment. The study of congenital HCMV infection Most scholars at home and abroad with neonatal urine and cord blood as the material, the infection rate of about 1 to 2%. This result is not helpful in the diagnosis of intrauterine diseases in early pregnancy. Therefore, it is necessary to study a method of prenatal diagnosis of congenital HCMV infection in early pregnancy, and it is important to prevent the birth of a fetus with a disease. We used polymerase chain reaction (PCR) for the first time in 68 HCMV infection of human embryos in early pregnancy, and the results showed that the HCMV gene was found in 16 samples of villus