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乙胺碘呋酮是作为抗心绞痛药物而发展起来的苯呋喃衍生物,由于降低冠状血管的阻力,增加冠状血流量而具有良好的心肌血液动力学效应。也具有非竞争性β—肾上腺受体阻滞作用。初步临床经验表明,对各种房性和室性快速性心律失常是有用的。在控制合并预激综合征之室上性快速性心律失常特别有用。其异常长的半衰期和副作用之罕见,使它在抗心律
Amiodarone, a benzofuran derivative developed as an anti-anginal drug, has good myocardial hemodynamic effects due to decreased coronary vascular resistance and increased coronary blood flow. Also has a non-competitive β-adrenergic receptor block. Preliminary clinical experience has shown that it is useful for a variety of atrial and ventricular tachyarrhythmia. It is particularly useful in controlling supraventricular tachyarrhythmias associated with Wolff-Parkinson-White syndrome. Its unusually long half-life and rare side effects make it an antiarrhythmic