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本文报告了用二次负荷剂量万古霉素i.p.治疗ESRF患者CAPD期间发生腹膜炎24例次。结果除1例外,其余23例全部治愈,治愈率96％。具体方法:初期处理用不加抗生素或肝素的腹透液2L,连续腹腔冲洗三次。对初期透出液涂片革兰氏染色细菌阳性者,用负荷剂量万古毒素(30mg/kg加入2 L腹透液中)i.p.,保留6小时后放出,继续常规腹透。于7天后再重用一次负荷量万古霉素。最初透出液涂片米发现细菌者,则在第一次万古霉素负荷量ip后,加用一次托布霉素或庆大霉
This article reports 24 cases of peritonitis occurring during CAPD in ESRF patients treated with twice-loading vancomycin i.p. Results except one case, the remaining 23 cases were cured, the cure rate was 96%. Specific methods: initial treatment without antibiotics or heparin dialysate 2L, continuous abdominal irrigation three times. On the initial liquid smear Gram-positive bacteria, with a loading dose of vancomycin toxins (30mg / kg added 2L dialysate) i.p., 6 hours after the release, to continue conventional dialysis. After 7 days, re-use the vancomycin load. Initially liquid smear found bacteria found in rice, then the first vancomycin load ip, plus once with tobramycin or gentamicin