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目的观察复方甘草酸苷治疗带状疱疹后遗神经痛的疗效。方法试验组给予阿昔洛韦600 mg口服,4次/d,复方甘草酸苷胶囊4粒,3次/d;对照组阿昔洛韦600 mg口服,4次/d;两组均给予甲钴胺片0.5 mg,3次/d,口服,酞丁胺擦剂外用,连续治疗10 d,如有疼痛,予呋喃硫胺片50 mg,3次/d,口服,停用阿昔洛韦3个月后判定疗效。结果试验组48例,治愈36例,治愈率为75.0%,总有效率为100%;对照组32例,治愈20例,治愈率为62.5%,总有效率为96.9%。试验组治愈率和总有效率均显著高于对照组(P<0.01)。结论治疗早期应用复方甘草酸苷可有效减少带状疱疹后遗神经痛的发生,有效减轻后遗神经痛的疼痛程度。
Objective To observe the efficacy of compound glycyrrhizin in the treatment of postherpetic neuralgia. Methods The experimental group was given acyclovir 600 mg orally 4 times a day, compound glycyrrhizin capsules 4 tablets 3 times a day, and the control group acyclovir 600 mg orally 4 times a day; Cobalt amine tablets 0.5 mg, 3 times / d, oral, topical phthalocyanine liniment for continuous treatment of 10 d, if pain, to furan thiamine 50 mg, 3 times / d orally, disable acyclovir After 3 months to determine the efficacy. Results In the experimental group, 48 cases were cured and 36 cases were cured. The cure rate was 75.0% and the total effective rate was 100%. In the control group, 32 cases were cured and the cure rate was 62.5%. The total effective rate was 96.9%. The cure rate and total effective rate of the experimental group were significantly higher than the control group (P <0.01). Conclusion The early application of compound glycyrrhizin can effectively reduce the incidence of postherpetic neuralgia and relieve the pain of post-operative neuralgia.