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目的:探讨内源性一氧化碳(CO)在老年呼吸系统感染性疾病中的变化。方法:80例老年患者分为肺炎组(30例)、慢喘支急发组(30例)、急支组(10例)、上感组(10例),测定血浆CO、TNF-α、IL-6浓度。结果:肺炎组、慢喘支急发组的CO、TNF-α水平明显高于上感组、急支组(P<0.001)。结论:CO在肺炎组、慢喘支急发组明显升高,可以作为观察病情严重程度的指标。
Objective: To investigate the changes of endogenous carbon monoxide (CO) in respiratory diseases of the elderly. Methods: 80 elderly patients were divided into pneumonia group (30 cases), chronic asthma group (30 cases), acute bronchitis group (10 cases) and Shanggan group (10 cases) IL-6 concentration. Results: The levels of CO and TNF-α in pneumonia group and chronic bronchitis group were significantly higher than those in Shanggan group and emergency group (P <0.001). Conclusion: CO in pneumonia group and chronic asthma group were significantly increased, which could be used as an indicator to observe the severity of the disease.