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本文报告了210例35岁以上妇女骨密度和血清参数的测定结果,发现骨质疏松时骨密度明显降低,血清参数中FSH、LH、BGP和AKP水平升高,E2和CT水平降低。这些变化和绝经年限有关。血清参数与骨密度的关系表现为:FSH、LH和AKP与BMD呈负相关关系,E2则呈正相关关系,BGP和CT无显著性相关关系。研究结果表明:BMD对骨质疏松症的诊断具有重要价值,而血清参数有着参考价值p<0.01,*P<0.05;与A、B组相比*P<0.01骨密度与血清参数相关关系见表3:血清FSH、LH和AKP与骨密度呈负相关关系,E2则呈正相关关系(P<0.001)。BGP和CT与骨密度无显著性相关关系。表3骨密度与血清参数相关关系3讨论骨质疏松主要是因骨质吸收超过骨质形成所引起单位体积骨量的减少。通常,当骨矿物质丢失达30%~50%以上时,才能显示于普通X线照片上。因此,单纯的X线检查对于骨质疏松症的早期诊断意义不大[3]。随着影像学的发展,光子吸收法测定骨密度得以广泛应用。无论是单吸收仪(SPA)、双光子吸收仪(DPA),还是双能X线吸收仪(DEXA),都更能较为准确地测定骨密度和骨矿含量。本研究结果显示用光子吸收仪测定?
In this paper, 210 cases of women over the age of 35 measured bone mineral density and serum parameters measured bone mineral density was significantly lower osteoporosis, serum parameters of FSH, LH, BGP and AKP levels, E2 and CT levels decreased. These changes are related to menopause. Serum parameters and the relationship between bone mineral density showed: FSH, LH and AKP negative correlation with BMD, E2 was a positive correlation between BGP and CT no significant correlation. The results show that: BMD is of great value in the diagnosis of osteoporosis, while the serum parameters have reference value p <0.01, * P <0.05; compared with A, B group Table 3 shows the relationship between BMD and serum parameters. Serum FSH, LH and AKP have a negative correlation with BMD and E2 with a positive correlation (P <0.001). There was no significant correlation between BGP and CT and BMD. Table 3, the relationship between bone mineral density and serum parameters 3 Discussion Osteoporosis is mainly due to bone resorption than bone formation caused by the reduction of bone volume per unit volume. Normally, when the bone mineral loss of more than 30% to 50%, can be displayed on the ordinary X-ray photos. Therefore, a simple X-ray examination for the early diagnosis of osteoporosis little significance [3]. With the development of imaging, photon absorption method for the determination of bone mineral density has been widely used. Whether single absorbers (SPA), two-photon absorbers (DPA), or dual-energy X-ray absorptiometry (DEXA), are more accurate and more accurate determination of bone mineral density and bone content. The results of this study show that photon absorption spectrometry