论文部分内容阅读
目的探讨三维动脉自旋标记技术(3D-ASL)联合磁共振血管成像(TOF MRA)在缺血性脑血管疾病中的应用效果。方法选取2013年8月—2015年8月广州中医药大学第一附属医院收治的缺血性脑血管疾病患者60例,观察患者TOF MRA下血管形态,并测量相对脑血流量(r CBF),比较3D-ASL和MRA诊断结果。结果缺血性脑血管疾病患者患侧平均r CBF低于健侧(P<0.05)。3D-ASL和TOF MRA对短暂性脑缺血发作(TIA)的诊断一致率为61.5%,对大面脑梗死的诊断一致率为100.0%,对小面积脑梗死的诊断一致率为29.6%。结论 3D-ASL可定量分析缺血性脑血管疾病患者脑组织血流灌注程度。3D-ASL和TOF MRA对大面积脑梗死的诊断一致性较高,而对TIA和小面积脑梗死的诊断一致性较差,二者联合应用可提高缺血性脑血管疾病的诊断准确率。
Objective To explore the application of three-dimensional arterial spin labeling (3D-ASL) and magnetic resonance angiography (TOF MRA) in ischemic cerebrovascular disease. Methods Sixty patients with ischemic cerebrovascular disease admitted to the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine between August 2013 and August 2015 were enrolled in this study. The vessel morphology under TOF MRA was observed and the relative cerebral blood flow (r CBF) Compare 3D-ASL and MRA diagnostic results. Results The average r CBF in affected side of ischemic cerebrovascular disease was lower than that in healthy side (P <0.05). The consistent diagnostic rates of TIA for 3D-ASL and TOF MRA were 61.5%, 100.0% for large-area cerebral infarction and 29.6% for small-area cerebral infarction. Conclusion 3D-ASL can quantitatively analyze the degree of perfusion of brain tissue in patients with ischemic cerebrovascular disease. The diagnostic accuracy of 3D-ASL and TOF MRA for large-area cerebral infarction is high, while the consistency of TIA and small-area cerebral infarction is poor. The combination of the two methods can improve the diagnostic accuracy of ischemic cerebrovascular disease.