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目的探讨外周动静脉同步换血治疗新生儿溶血病的临床疗效。方法本研究选择18例2009年7月—2011年10月在濮阳市妇幼保健院新生儿重症监护室住院的新生儿溶血病患儿,采用外周动静脉同步换血治疗,换血前后检测肝功能检查,观察换血前后血清总胆红素、间接胆红素、直接胆红素变化。结果行外周动静脉同步换血后,总胆红素、间接胆红素、直接胆红素均显著减低,与换血前相比,t值分别为14.86、13.75、11.56,P均<0.01,其差异有统计学意义。结论外周动静脉同步换血治疗新生儿溶血病,方法简单、方便,疗效确切。
Objective To investigate the clinical efficacy of peripheral arteriovenous exchange transfusion in the treatment of neonatal hemolytic disease. Methods 18 cases of neonatal hemolytic disease hospitalized in neonatal intensive care unit of Puyang Maternal and Child Health Hospital from July 2009 to October 2011 were enrolled in this study. Peripheral arterial and venous exchange transfusion was used to treat liver function tests before and after transfusion, Observed before and after the exchange of serum total bilirubin, indirect bilirubin, direct bilirubin changes. Results After exchanging peripheral arterial and venous blood synchronously, total bilirubin, indirect bilirubin and direct bilirubin were significantly decreased, t values were 14.86, 13.75 and 11.56, respectively There is statistical significance. Conclusion Peripheral arteriovenous exchange transfusion of blood in the treatment of neonatal hemolytic disease, the method is simple, convenient and effective.