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目的 评价保守手术后复发的重症子宫内膜异位症 (内异症 )根治术时实施自体卵巢组织移植的价值。方法 常州市妇幼保健院 1997年 2月至 2 0 0 1年 12月对 2 5例子宫内膜异位症保守手术后出现复发的Ⅳ期内异症患者 ,施行根治术或剩余卵巢切除术 ,术时将自体卵巢组织片移植于大网膜之中。术后测定卵泡刺激素(FSH)、黄体生成激素 (LH)和雌二醇 (E2 )。E2 水平上升后 ,测定基础体温 ,做阴道脱落细胞学检查。结果 2 5例患者中 ,2 0例术后 4～ 6个月E2 水平上升 ,卵巢组织移植成活率为 80 0 %。卵巢功能维持时间最长者已达 4年以上。仅 1例出现内异症复发 ,复发率为 5 0 %。结论 对卵巢组织破坏严重的复发性重症内异症患者 ,根治术时实施卵巢组织移植是保留卵巢功能 ,减少内异症复发的有效方法。
Objective To evaluate the value of autologous ovarian tissue transplantation in the treatment of severe endometriosis (endometriosis) after conservative surgery. Methods Changzhou MCH hospital from February 1997 to December 2001 on 25 cases of endometriosis recurrence after conservative surgery in patients with stage Ⅳ endometriosis, radical or residual ovariectomy, Surgery will be self-ovarian tissue transplanted into the omentum. Follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E2) were measured after operation. E2 level rise, the determination of basal body temperature, vaginal cytology. Results Twenty-five patients, 20 cases of E2 increased 4-6 months after operation, the survival rate of ovarian tissue transplantation was 80%. Ovarian function to maintain the longest time for more than 4 years. Only one case of recurrence of endometriosis, the recurrence rate was 50%. Conclusion In patients with recurrent severe endometriosis with severe destruction of ovarian tissue, transplantation of ovarian tissue at the time of radical operation is an effective way to preserve ovarian function and reduce the recurrence of endometriosis.