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为了研究平均血小板体积（ＭＰＶ）增大与脑梗塞（ＣＩ）的因果关系，用全自动血细胞分析仪对５０例Ⅱ型糖尿病、６０例高血压病Ⅱ期以及２５例糖尿病并发ＣＩ和４３例高血压病并发ＣＩ患者静脉血ＭＰＶ进行了观察，并与７０例同期住院者（对照组）进行比较。结果：糖尿病及其并发ＣＩ时ＭＰＶ均较对照组明显增大（Ｐ均＜０．０１），高血压病及其并发ＣＩ者ＭＰＶ也增大（Ｐ均＜０．０５），但不及糖尿病时明显（Ｐ＜０．０５），并发ＣＩ后ＭＰＶ无进一步变化。提示ＭＰＶ增大发生在脑梗塞之前，可能是糖尿病、高血压病患者发生梗塞的始动因素之一。
To investigate the causal relationship between increased mean platelet volume (MPV) and cerebral infarction (CI), 50 patients with type 2 diabetes mellitus, 60 with hypertension and 25 with diabetes mellitus (CI) and 43 with high Venous blood MPV in patients with blood pressure complicated with CI was observed and compared with 70 hospitalized patients in the same period (control group). Results: Compared with the control group, the MPV of diabetes mellitus and its complicated CI were significantly increased (all P <0.01), and the MPV of hypertension and its concurrent CI were also increased (all P <0.05) (P <0.05), and no further changes in MPV after CI. Tip MPV increased occurred in the cerebral infarction before, may be diabetes, hypertension in patients with one of the initiating factor of infarction.