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患者女,62岁,阻塞性黄疸,在连续硬膜外麻醉下行总胆管空肠吻合,缝合腹膜时因肌紧张而给予司考林100毫克,引起迁延性呼吸抑制,总的呼吸抑制时间为72小时。琥珀酰胆硷引起的迁延性呼吸抑制,多与血桨胆硷脂酶先天性异常或后天量的减少有关。作者复习了有关文献,认为本例迁延性呼吸抑制的原因,可能与患者全身情况差,如贫血,肝功中度损害伴重度黄疸;及因此而致血桨胆硷脂酶活性低(术后第四天胆硷酯酶活性
Female, 62 years old, obstructive jaundice, underwent biliary jejunal anastomosis under continuous epidural anesthesia and received 100 mg of Division Colin due to muscle tension during suturing of the peritoneum, causing persistent respiratory depression with a total respiratory depression of 72 hours . Succinylcholine-induced delayed respiratory depression, and more blood and cholelithiasmic congenital anomalies or decreased amount of acquired. The authors reviewed the literature and concluded that the causes of persistent respiratory depression in this case may be associated with poor systemic conditions such as anemia, moderate liver damage with severe jaundice, and low plasma cholinesterase activity (postoperative The fourth day cholinesterase activity