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自1990年起,我们对活动性消化性溃疡伴幽门螺旋菌阳性患者,进行了分组对比治疗观察.现将结果报告如下.资料与方法 本组共50例,均为住院或门诊病人,其中男42例,女8例.年龄16～72岁,平均44岁.全部病人均经胃镜检查诊断为活动性溃疡,遂即取胃窦粘膜4块,分别进行尿素酶试验和组织学、细菌学检查,幽门螺旋菌(HP)阳性者,按下述三组分别接受不同药物治疗.A组:胶态次拘橼酸铋冲剂(简称CBS),每日4次,每次110mg.B组:雷尼替丁150mg,每日2次,加用痢特灵100mg,每日3次.C组:雷尼替丁150mg,每日2次.疗程为6周,疗程结束1周内按治疗前的方法进行复查,判定疗效.疗效观察:三组病人的自觉症状均明显改善或消失,无统计学上的差异(P>0.05).
Since 1990, we have active peptic ulcer patients with Helicobacter pylori positive treatment, the group compared the treatment of observation.The results are reported as follows.Materials and methods of this group a total of 50 patients were hospitalized or outpatient, male 42 cases and 8 females.Ages ranging from 16 to 72 years old, average 44 years old.All patients were diagnosed as active ulcer by gastroscopy, then take antral mucosa 4, respectively, urease test and histology, bacteriological examination , Helicobacter pylori (HP) were positive, according to the following three groups were treated with different drugs.A group: Colloidal Subang citrate bismuth (CBS), 4 times a day, each time 110mg.B group: Ray Nidotidine 150mg, 2 times a day, plus furazolidone 100mg, 3 times a day.C group: ranitidine 150mg, 2 times a day.Courses for 6 weeks, the end of the course of treatment within 1 week before treatment Methods: The curative effect was observed.Efficacy of the three groups of patients’ symptoms were significantly improved or disappeared, with no statistical difference (P> 0.05).