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目的探讨脑钠素(BNP)水平与心功能的相关性,进一步说明BNP测定对心力衰竭(以下简称心衰)的重要性。方法随机选择56例住院心衰患者及52例无器质心脏病患者作为研究对象。入院当日采集血标本以备血浆BNP、血糖、血脂等检查,采用ELISA法测定血浆BNP水平,血浆BNP水平与心功能相关性采用SPSS10.0软件进行分析。结果随着心衰程度加重,血浆BNP水平逐渐升高,患者BNP降低值与左室射血分数(LVEF)存在良好负相关。结论CHF患者血浆BNP浓度升高,且随CHF程度的增加而显著升高。
Objective To investigate the relationship between BNP level and cardiac function and to further elucidate the importance of BNP in heart failure (HF). Methods 56 cases of hospitalized patients with heart failure and 52 cases of non-structural heart disease were randomly selected as the research object. Blood samples were collected on the day of admission to prepare plasma BNP, blood glucose, blood lipids and other tests, plasma BNP levels were measured by ELISA, plasma BNP levels and cardiac function using SPSS10.0 software for analysis. Results With the worsening of heart failure, plasma BNP levels gradually increased. There was a negative correlation between the decrease of BNP and left ventricular ejection fraction (LVEF). Conclusion The plasma BNP level in patients with CHF is significantly higher than that in CHF patients.