参芪降糖颗粒联合格列美脲治疗糖尿病门诊患者的疗效及安全性分析

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目的:探讨参芪降糖颗粒联合格列美脲应用于糖尿病门诊患者的临床疗效及安全性。方法:选取2014年3月—至2016年4月本院门诊收治的110例2型糖尿病,分为观察组与对照组,对照组患者单纯给予格列美脲治疗,观察组患者给予参芪降糖颗粒联合格列美脲治疗,对比患者临床疗效、治疗前后血糖相关指标变化及临床症状评分,同时观察两组患者不良反应发生情况。结果:观察组患者的总有效率明显高于对照组(P<0.05);治疗后观察组与对照组患者的餐后2 h血糖、空腹血糖、糖化血红蛋白水平及临床症状评分均较治疗前明显降低,治疗后,观察组患者的血糖相关指标及临床症状评分均明显低于对照组(P<0.05)。结论:参芪降糖颗粒联合格列美脲治疗2型糖尿病门诊患者能够明显改善患者血糖水平及临床症状,疗效显著,安全性高,值得临床推广应用。 Objective: To investigate the clinical efficacy and safety of Shenqijiangtang Granules combined with glimepiride in patients with diabetes clinic. Methods: A total of 110 type 2 diabetic patients treated in our hospital from March 2014 to April 2016 were divided into observation group and control group. Patients in the control group were treated with glimepiride alone. Patients in the observation group were given Shenqi Jiang Sugar particles combined with glimepiride treatment, compared the clinical efficacy of patients before and after treatment, changes in blood glucose-related indicators and clinical symptom score, while observing the two groups of patients with adverse reactions. Results: The total effective rate of the observation group was significantly higher than that of the control group (P <0.05). The postprandial 2-h postprandial blood glucose, fasting blood glucose, glycosylated hemoglobin and clinical symptom scores of the observation group and the control group were significantly higher than those before treatment After treatment, the patients in the observation group had significantly lower blood glucose related indicators and clinical symptom scores than those in the control group (P <0.05). Conclusion: Shenqijiangtang granules combined with glimepiride treatment of type 2 diabetes clinic patients can significantly improve blood glucose levels and clinical symptoms in patients with significant effect, high safety, it is worth promoting the clinical application.
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