TWENTY-FOUR HOUR DIURNAL CURVE COMPARISON OF COMMERCIALLY AVAILABLE BIMATOPROST 0.03% VERSUS TIMOLOL

• 作 者: D.G.Day E.D.Sharpe C.J.Beischel J.N.Leech J.A.Stewart W.C.Stewart
• 机 构: Omni Eye Services, GA,,Ophthalmology Consultants, SC,,West Ashley Medical Center, SC,,Pharmaceutical
• 出 处: 国际眼科杂志
• 发表日期: 2003年01期
• 关键词: glaucoma hypertensive maleate versus crossover evening ocular twice minus trough

Purpose: To evaluate the efficacy and safety of bimatoprost 0.03 percent given every evening versus timolol maleate 0.5 per-cent/dorzolamide 2 percent fixed combination (TDFC) given twice daily in open-angle glaucoma and ocular hypertensive patients. Design: A single-masked, two center, crossover comparison with two eight-week treatment periods following a four-week medicine free run-in period. Diurnal curve intraoc-

Purpose: To evaluate the efficacy and safety of bimatoprost 0.03 percent given every evening versus timolol maleate 0.5 per-cent / dorzolamide 2 percent fixed combination (TDFC) given twice daily in open-angle glaucoma and ocular hypertensive patients. Design: A single-masked , two center, crossover comparison with two eight-week treatment periods following a four-week medicine free run-in period. Diurnal curve intraoc-