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目的观察阿托伐他汀联合阿司匹林对脑梗死患者颈动脉斑块及脑梗死复发的影响。方法将80例存在颈动脉斑块的脑梗死患者随机分为两组,每组均为40例,均于治疗前及治疗6个月后检查颈动脉彩超,治疗组:口服阿托伐他汀钙片及阿司匹林肠溶片;对照组:口服阿司匹林肠溶片,治疗6个月后分析阿托伐他汀联合阿司匹林对脑梗死患者颈动脉斑块及脑梗死复发的影响,并作统计学分析。结果治疗6个月后治疗组不稳定斑块率下降,与治疗前相比差异有统计学意义(P<0.05),与对照组相比差异有统计学意义(P<0.05);治疗组脑梗死复发率小,与对照组相比差异有统计学意义(P<0.05)。结论阿托伐他汀联合阿司匹林能够稳定颈动脉斑块,减少脑梗死复发。
Objective To observe the effect of atorvastatin combined with aspirin on the recurrence of carotid artery plaque and cerebral infarction in patients with cerebral infarction. Methods Eighty patients with cerebral infarction with carotid artery plaque were randomly divided into two groups, 40 cases in each group. Carotid ultrasonography was performed before treatment and 6 months after treatment. The treatment group: oral atorvastatin calcium And aspirin enteric-coated tablets; control group: oral aspirin enteric-coated tablets, the treatment of 6 months after the analysis of atorvastatin combined with aspirin in patients with cerebral infarction carotid plaque and cerebral infarction recurrence, and for statistical analysis. Results After 6 months of treatment, the unstable plaque rate in the treatment group decreased significantly compared with that before treatment (P <0.05), and the difference was statistically significant compared with the control group (P <0.05) The recurrence rate of infarction was small, compared with the control group, the difference was statistically significant (P <0.05). Conclusions Atorvastatin combined with aspirin can stabilize the carotid artery plaque and reduce the recurrence of cerebral infarction.