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目的分析奥曲肽联合凝血酶治疗肝硬化合并上消化道出血的临床疗效及安全性。方法 100例肝硬化合并上消化道出血患者,采用随机数字表法分为实验组和对照组,各50例。对照组使用奥曲肽治疗,实验组联合使用奥曲肽和凝血酶治疗,对比两组临床疗效及安全性。结果实验组总有效率高于对照组(P<0.05);实验组止血时间短于对照组(P<0.05)。结论奥曲肽与凝血酶联合使用治疗肝硬化合并上消化道出血效果明显,能有效缩短出血时间,提高临床疗效,具有较高推广和借鉴价值。
Objective To analyze the clinical efficacy and safety of octreotide combined with thrombin in the treatment of cirrhosis and upper gastrointestinal bleeding. Methods One hundred patients with cirrhosis complicated with upper gastrointestinal bleeding were divided into experimental group and control group by random number table method, 50 cases each. The control group was treated with octreotide, and the experimental group was treated with octreotide and thrombin. The clinical efficacy and safety were compared between the two groups. Results The total effective rate of the experimental group was higher than that of the control group (P <0.05). The bleeding time of the experimental group was shorter than that of the control group (P <0.05). Conclusion Combined use of octreotide and thrombin in the treatment of cirrhosis combined with upper gastrointestinal bleeding has obvious effect, which can effectively shorten the bleeding time and improve the clinical curative effect, with a high promotion and reference value.