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患者,男,24岁,农民,6年前颊部、双手背出现红斑,自觉搔痒,日晒后加重,秋冬缓解。1年前开始下唇肿胀,初为紫红色斑片,覆厚痂,表面起小水疱,疼痛,疱破后溃烂面逐渐向外扩大,外翻。近6年来双膝关节常疼痛,吸烟5～6支/日.检查面部、双颊部皮肤为深褐色斑,手背、鼻背、颊部间有脱色斑.上唇肿胀覆黄色痂皮,下唇溃烂呈菜花状外翻约5.5×3×2厘米,表面覆脓血痂。化验:尿
Patient, male, 24 years old, farmer, 6 years ago, cheeks, red back with both hands, itching, aggravating after sun exposure, ease in autumn and winter. 1 year ago began to lower lip swelling, the beginning of the purple patches, thick thick crust, the surface of small blisters, pain, blisters after the ulcer surface gradually expand outward, valgus. Over the past 6 years, the knee joint often pain, smoking 5 to 6 / day .Check the face, cheek skin dark brown spots, back of the hand, nose and back, between the cheeks discolored spots .Light lip swelling yellow crust, under Lip ulcer was cauliflower everted about 5.5 × 3 × 2 cm, the surface covered pus blood scab. Laboratory: urine