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左旋门冬酰胺酶(L-Asp)广泛应用于儿童急性淋巴细胞性白血病(ALL)的联合化疗,显著提高了患儿的完全缓解率和长期无病生存率。在临床治疗过程中最常见的并发症是低蛋白血症,白蛋白水平的变化能引起机体多种脏器功能损害,并可影响化疗药物在体内的代谢,因此研究化疗过程中白蛋白
L-asparaginase (L-Asp) is widely used in children with acute lymphoblastic leukemia (ALL) combined chemotherapy, significantly improve the children’s complete remission rate and long-term disease-free survival rate. The most common complication in clinical treatment is hypoalbuminemia. Changes in albumin levels can cause functional impairment of various organs in the body and can affect the metabolism of chemotherapeutic drugs in vivo. Therefore, the study of albumin