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前言多肽具有调节机体生理功能和为机体提供营养的双重功效,它几乎影响着人体的一切代谢合成。一种肽含有的氨基酸少于10个称为寡肽,超过的就称为多肽。1902年,伦敦大学医学院的两位生理学家Bayliss和Starling在动物胃肠里发现了胰泌素~([1])。这是人类第一次发现的多肽物质。1965年我国科学家完成了世界上第一次人工合成多肽——牛结晶胰岛素。脑啡肽及阿片样肽相继发现使神经肽的研究进入高潮,开启了多肽研究的新时代。
Introduction Peptides have the dual effect of regulating the physiological function of the body and providing nutrition to the body, which affects almost all metabolic synthesis of the body. A peptide contains less than 10 amino acids called oligopeptides, more than known as the polypeptide. In 1902 Bayliss and Starling, two physiologists at the University of London School of Medicine, discovered secretin in the gastrointestinal tract of animals [1]. This is the first human discovery of the polypeptide material. 1965 Chinese scientists completed the world’s first artificial synthetic peptide - bovine insulin. Enkephalin and opioid peptides have been found in neuropeptide research culminated, opened a new era of peptide research.