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笔者报告了1975～2008年本院收治的经病理证实的肛管直肠恶性黑色素瘤(ARMM)23例。对23例ARMM患者分别行根治性切除术(Mile’s术)和局部切除术及冰冻治疗,术后并辅以放疗、化疗、及生物治疗。19例患者获随访,随访时间8个月～5年。随访结果,Miler`s术组中位生存期为25.4个月,局部切除组及冰冻治疗组中位生存期为11个月,化疗组中位生存期为6个月。作者认为患者生存率的关键是早期治疗。并对ARMM的病因、临床诊断及其治疗进行了讨论。
The author reported from 1975 to 2008 admitted to our hospital pathologically confirmed 23 cases of anorectal malignant melanoma (ARMM). Twenty-three patients with ARMM underwent radical resection (Mile’s surgery) and local resection and cryotherapy. Postoperative radiotherapy, chemotherapy and biotherapy were performed. 19 patients were followed up for 8 months to 5 years. The median follow-up time was 25.4 months in Miler`s surgery group, 11 months in partial resection group and cryotherapy group, and 6 months in chemotherapy group. The authors believe that the key to patient survival is early treatment. The etiology, clinical diagnosis and treatment of ARMM were discussed.