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目的:观察匹维溴胺联合乳果糖配合心理干预治疗功能性便秘的临床疗效。方法:将120例功能性便秘患者随机分为两组,对照组60例,给予乳果糖(l0ml/次,3次/天),匹维溴胺(50mg/次,3次/天)。治疗组60例在对照组基础上同时给予心理干预治疗,四周后,比较两种治疗方案的疗效。结果:治疗组有效率为96.67%,对照组治疗组有效率为76.67%,两组对比差异有统计学意义(P<0.05),两组均未发生不良反应。结论:匹维溴胺联合乳果糖配合心理干预治疗功能性便秘,取得满意的临床效果。
Objective: To observe the clinical efficacy of pirenzolamide combined with lactulose and psychological intervention in the treatment of functional constipation. Methods: One hundred and twenty patients with functional constipation were randomly divided into two groups. The control group was given lactulose (l0ml / time, 3times / day) and pinaverium bromide (50mg / time, 3times / day). 60 cases in the treatment group were treated with psychological intervention on the basis of the control group. After four weeks, the curative effect of the two treatment plans was compared. Results: The effective rate of the treatment group was 96.67%, while that of the control group was 76.67%. The difference between the two groups was statistically significant (P <0.05). No adverse reactions occurred in both groups. Conclusion: Pivoxil and lactulose with psychological intervention in the treatment of functional constipation, and achieved satisfactory clinical results.