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仅在高血压脑病和子痫等几种情况需要在2小时内经肠道外给药降低血压。如果血压下降太快会引起心、脑和肾的局部缺血以及失明。除上述紧急情况外,口服治疗已足够。本研究采用口服单剂心脏选择性β阻滞剂——氨酰心安(atenolol)在非常严重的高血压中平稳地控制血压,避免了血压骤降。10例血压超过200/130mmHg 患者(男8例,女2例),年龄为15～62(平均46)岁。其中9例为恶性高血压,仅1例接受过治疗。患者口服单剂氨酰心安100mg,服药后12小时内每2小时测血压1次.
Only in hypertensive encephalopathy and eclampsia and other circumstances need to be parenteral administration within 2 hours to reduce blood pressure. If the blood pressure drops too fast can cause heart, brain and kidney ischemia and blindness. In addition to the above emergency situations, oral treatment is sufficient. In our study, atenolol, a single oral dose of heart-selective beta-blocker, was used to control blood pressure smoothly in very severe hypertension and to avoid sudden drop in blood pressure. 10 patients with blood pressure over 200 / 130mmHg (8 males and 2 females), aged 15 to 62 (average 46 years). Of these, 9 were malignant and only 1 received treatment. Patients oral single-dose atenolol 100mg, within 12 hours after taking medication every 2 hours to measure blood pressure 1.