论文部分内容阅读
９８例己确诊为鼻咽癌病例随机分为单纯放射组（４８例）和放射治疗综合应用顺铂组（５０例）。放射治疗全部采用同中心治疗，总剂量７０Ｇｙ／３５－３７次／７—８周。顺铂自放射开始后第二天使用，１次／周，２０ｍｇ／ｍ２／次。在治疗结束后三月评价，放射联合顺铂组和单纯放射组的原发肿瘤完全消退率分别为９２％和６８．７５％，颈部转移灶的完全消退率分别为９０．６％和６９．４％，两组经统计学处理均有显著性差异。随访三年（中位随访期４０月），三年生存率分别为综合治疗组８３％和单纯放射射组７６％。两组急性反应和后期反应无显著差异，所有病人均能耐受而完成治疗计划。
98 cases of nasopharyngeal carcinoma that had been diagnosed as nasopharyngeal carcinoma were randomly divided into simple radiotherapy group (48 cases) and radiotherapy combined with cisplatin group (50 cases). Radiotherapy all with concentric treatment, the total dose of 70Gy / 35-37 times / 7-8 weeks. Cisplatin was used the day after the start of radiotherapy, once a week, 20 mg / m2 / time. In the March evaluation after the end of treatment, the complete regression rate of the primary tumors in radiotherapy combined with cisplatin and radiotherapy alone was 92% and 68.75%, respectively, and the complete regression rates of cervical metastases were 90.6% and 69% .4%, two groups were statistically significant differences. Three years follow-up (median follow-up 40 months), the three-year survival rates were 83% in the combination therapy group and 76% in the radiotherapy alone group, respectively. No significant difference between the two groups of acute and late reactions, all patients can tolerate and complete the treatment plan.