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目的观察卡维地洛对充血性心力衰竭的临床疗效。方法入选入院治疗的100例充血性心力衰竭患者。卡维地洛组50例,常规组50例。口服卡维地洛起始剂量2.5 mg,以后渐增至10 mg,2次/d,总疗程6个月。给药前停服其他β受体阻滞剂1周以上。治疗前及治疗后做超声心动图,评价心功能观察并记录不良反应。结果治疗后两组相比,卡维地洛组在FS、LVEF改善方面优于常规治疗组(P<0.05)。结论小剂量卡维地洛治疗充血性心衰安全有效。
Objective To observe the clinical effect of carvedilol on congestive heart failure. Methods 100 patients admitted to hospital for treatment of congestive heart failure. 50 cases of carvedilol group, 50 cases of conventional group. Oral carvedilol initial dose of 2.5 mg, later increased to 10 mg, 2 times / d, the total course of 6 months. Stop taking other beta-blockers for more than 1 week prior to dosing. Before treatment and after treatment, do echocardiography, evaluation of cardiac function and record adverse reactions. Results After treatment, the carvedilol group was superior to the conventional treatment group in improving FS and LVEF (P <0.05). Conclusions Low-dose carvedilol is safe and effective in treating congestive heart failure.