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白细胞介素32(IL-32)是近年来发现的一种炎性细胞因子,主要由T淋巴细胞、自然杀伤细胞、单核细胞和上皮细胞等产生。IL-32诱导细胞因子的产生,在自身免疫方面起重要作用。IL-32参与慢性阻塞性肺疾病的特异性自身免疫炎性反应。认识二者关系有利于为临床治疗慢性阻塞性肺疾病提供新的思路。
Interleukin 32 (IL-32) is an inflammatory cytokine found in recent years and is mainly produced by T lymphocytes, natural killer cells, monocytes and epithelial cells. IL-32 induces cytokine production and plays an important role in autoimmunity. IL-32 is involved in the specific autoimmune inflammatory reaction in chronic obstructive pulmonary disease. Understanding the relationship between the two is beneficial to provide new ideas for clinical treatment of chronic obstructive pulmonary disease.