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为了解海洛因依赖者ＴＴ 病毒感染状况、研究其致病性及病毒特征，探讨感染传播途径，采用巢式ＰＣＲ 和ＥＬＩＳＡ 法检测２８６ 例海络因依赖者血清ＴＴ病毒ＤＮＡ 和抗体ＩｇＧ。结果显示：２８６ 例血清标本ＴＴ 病毒ＤＮＡ 和抗体ＩｇＧ的阳性率分别为７－０ ％ 和９－４％ ；无一例标本同时检出ＴＴ 病毒ＤＮＡ 和抗体ＩｇＧ；ＡＬＴ 升高和正常组ＴＴ 病毒感染阳性率差异无显著性（ Ｐ＞０－０５） 。结果显示：海洛因依赖者存在ＴＴ 病毒感染和无症状携带状态，感染不依赖其它肝炎病毒而单独存在；ＴＴ病毒可能是一种新的自限性ＤＮＡ病毒，其对肝脏的损害作用不确切；静脉注射不是海洛因依赖者ＴＴ病毒感染的主要途径。
In order to understand the status of TT virus infection in heroin addicts, the pathogenicity and virus characteristics of heroin addicts were investigated. The transmission routes of infection were also explored. The serum TT virus DNA and IgG were detected by nested PCR and ELISA in 286 cases of heroin addicts. The results showed that the positive rates of TT virus DNA and antibody IgG in 286 serum samples were 7-0% and 9-4%, respectively. None of the samples detected TT virus DNA and antibody IgG simultaneously. Elevated ALT and normal group TT virus infection The positive rate was not significantly different (P> 0-05). The results showed that there was TT virus infection and asymptomatic carrier status in heroin dependent patients. The infection was independent of other hepatitis viruses. The TT virus may be a new self-limited DNA virus with impaired liver function. Injection is not the main route of TT virus infection in heroin addicts.