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[目的]探讨基于营养风险评估的个体化营养干预对老年晚期结直肠癌化疗患者营养状况及生活质量的影响.[方法]选择2014年4月至2016年4月本院收治的老年晚期结直肠癌化疗患者114例为研究对象,采用随机数字表法分为观察组和对照组,每组各57例.对照组采用常规护理干预,观察组在对照组的基础上采用基于营养风险评估的个体化营养干预,比较两组患者营养状况和生活质量.[结果]观察组血清前白蛋白(PA)、白蛋白(ALB)、血红蛋白(Hb)等指标均明显高于对照组(P<00.5);认知功能、躯体功能、社会角色功能、情绪功能等生活质量评分明显高于对照组(P<00.5).[结论]基于营养风险评估的个体化营养干预可以显著改善老年晚期结直肠癌化疗患者营养状况,提高患者的生活质量.“,”[Objective]To investigate the effects of individualized nutritional intervention based on nutritional risk as-sessment on nutritional status and life quality of elderly chemotherapy patients with advanced colorectal cancer .[Methods]A total of 114 cases of elderly chemotherapy patients with advanced colorectal cancer admitted to hospital from April 2014 to April 2016 were selected as the research objects and divided into the observation group and the control group using the random number table method ,with 57 cases in each group .Patients in the control group received routine nursing interven-tion ,while patients in the observation group were received individual nutritional intervention based on nutritional risk as-sessment .The nutritional status and life quality of patients in the two groups were compared .[Results]The levels of ser-um pre-albumin (PA) ,albumin (ALB) ,hemoglobin (Hb) and other indicators in the observation group were significant-ly higher than those in the control group ( P <00.5);the scores of life quality including cognitive function ,physical func-tion ,social function and emotional role were significantly higher than those in Control Group ( P <00.5) .[Conclusion]In-dividualized nutritional intervention based on nutritional risk assessment can significantly improve the nutritional status as well as the life quality of elderly chemotherapy patients with advanced colorectal cancer .