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将本院近两年来的DE足患者68例随机分为治疗组(35例)和对照组(33例),两组严重程度的差异均无显著性。治疗组在对照组治疗基础上加予口服贝前列素钠(德纳,40微克,一天三次)及肌肉注射甲钴胺(弥可保,500微克,一天一次)治疗,共四周。结果治疗组总有效率达77.1%,明显高于对照组48.4%(P<0.05)。治疗后两组足背动脉血流速度及腓总神经感觉传导速度均有显著性差异(P<0.05)。结论贝前列素钠联合甲钴胺治疗糖尿病足安全有效。现选用贝前列素钠联合甲钴胺治疗我院近两年来的35例糖尿病足患者,并和对照组33例进行对比观察,现报告如下:
Sixty-eight patients with DE in the past two years in our hospital were randomly divided into treatment group (n = 35) and control group (n = 33). There was no significant difference between the two groups in severity. The treatment group was given oral treatment with beraprost sodium (Dana, 40 micrograms three times a day) and intramuscular injection of mecobalamin (Miocao, 500 micrograms once a day) for 4 weeks on the basis of the control group. Results The total effective rate in the treatment group was 77.1%, which was significantly higher than that in the control group (48.4%, P <0.05). After treatment, the blood flow velocity of the dorsalis pedis artery and the sensory velocity of the common peroneal nerve were significantly different (P <0.05). Conclusion Bebeprost sodium combined with methylcobalamin in the treatment of diabetic foot is safe and effective. Are selected beraprost sodium combined with mecobalamin treatment of 35 cases of diabetic foot patients in our hospital in the past two years, and compared with the control group of 33 cases, the report is as follows: