肥皂荚Gymnocladus chinensis Baill.中两个三萜皂苷的结构鉴定(英文)

• 作 者: 王刊 付宏征
• 机 构: 北京大学天然药物及仿生药物国家重点实验室,
• 出 处: Journal of Chinese Pharmaceutical Sciences
• 发表日期: 2009年02期
• 关键词: glucopyranosyl dihydroxy 化合物 三萜皂苷 COSY saponins trimethyl 英文 pyridine moiety

从肥皂荚Gymnocladus chinensis Baill.提取出两个三萜皂苷类化合物(化合物I与II),其中化合物I为新化合物,通过核磁方法,鉴定其为2β,23-dihydroxy-acacic acid-3-O-α-L-arabinopyranosyl-21-O-{(6S)-2-E-2,6-dimethyl-6-O-[4-O-(6S)-2-E-2,6-dimethyl-6-O-β-D-glucopyranosyl-α-L-arabinopyranosyl-2,7-octadienoyl}-28-O-β-D-xylopyranosyl(1→3)-β-D-xylopyranosyl(1→4)-α-L-rhamnopyranosyl(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside。

Two triterpene saponins (compounds I and II) were extracted from Gymnecladus chinensis Baill. The compound I was a new compound and was identified as 2β,23-dihydroxy-acacic acid-3-O by nuclear magnetic method. α-L-arabinopyranosyl-21-O-{(6S)-2-E-2,6-dimethyl-6-O-[4-O-(6S)-2-E-2,6-dimethyl-6- O-β-D-glucopyranosyl-α-L-arabinopyranosyl-2,7-octadienoyl}-28-O-β-D-xylopyranosyl(1→3)-β-D-xylopyranosyl(1→4)-α-L -rhamnopyranosyl (1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside.