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许多神经原性直立性低血压患者,因站立时眩晕、晕厥而丧失劳动力,曾用多种方法治疗疗效均不满意。用含有酪胺的食物及单胺氧化酶抑制剂治疗,因酪胺含量易变,疗效也不肯定。本文6例采用酪胺的化学制剂与单胺氧化酶抑制剂超苯环丙胺(Tranylcypromine)治疗,效果良好。 6例中女2例,男4例,年龄25～72岁。有眩晕、晕厥症状3～21年。其中4例无其它神经系统疾患(特发性直立性低血压),1例伴震颤麻痹,另1例伴小脑性共济失调及皮质脊髓束功能障碍。治疗方法是第1周服超苯环丙胺10毫克,3次/日。第2周加至20毫克,3次/日。两周后静滴酪胺一个剂量,并观察血压反应。随后对静滴酪胺有反应的5例开始用超苯环丙胺加酪胺的胶囊(每胶囊含酪胺5或10毫克)口服,3次/日。每半小时测卧位与立位血压一
Many patients with neurogenic orthostatic hypotension, due to standing vertigo, syncope and loss of labor, have used a variety of methods to treat the efficacy are not satisfied. Treated with tyramine-containing foods and monoamine oxidase inhibitors, the curative effect is uncertain due to the variable content of tyramine. In this paper, 6 cases with tyramine chemical and monoamine oxidase inhibitor trabenzopyrine (Tranylcypromine) treatment, the effect is good. 6 cases of female 2 cases, 4 males, aged 25 to 72 years. Have dizziness, syncope symptoms 3 to 21 years. Of these, 4 had no other neurological disorders (idiopathic orthostatic hypotension), 1 had paralysis with paralysis, and 1 had cerebellar ataxia and corticospinal tract dysfunction. Treatment is the first week of 10 mg of benzene sulfamethoxazole, 3 times / day. 2 weeks to 20 mg, 3 times / day. After two weeks of intravenous infusion of a dose of tyramine, and observe the blood pressure response. Subsequent to intravenous tyramine reactions in 5 patients started with hybrimethylene plus tyramine capsules (containing tyramine per capsule 5 or 10 mg) orally, 3 times / day. Every half hour to measure lying position and standing blood pressure one