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目的研究妇女孕期所从事的职业对生殖结局（包括妊娠结局和新生儿情况）及妊娠和分娩并发症的影响。方法应用医院产科记录，结合随访调查。资料来源于北京市８个医院１９９２年５月～１９９３年４月期间分娩的１２２２４名初产妇的产科记录以及于产妇出院前进行随访调查的记录。经ｌｏ－ｇｉｓｔｉｃ回归分析，调整了孕时年龄、孕期吸烟、饮酒和自然流产史等潜在的混杂因素后，按职业类别对其妊娠经过和生殖结局进行分析。结果工人中，妊娠高血压综合征、低出生体重、宫内发育迟缓及产后出血的发生率显著高于平均水平。专业技术人员中先兆流产、妊娠贫血、死胎死产、宫缩无力，农民中过期产、新生儿窒息，家庭妇女中低出生体重，办事人员中妊娠贫血，管理工作人员中宫缩无力等的发生率，显著高于平均水平。结论妇女孕期从事的职业与不良妊娠经过和生殖结局之间有一定关联。
Objective To study the effects of occupation during pregnancy on reproductive outcomes (including pregnancy outcome and neonatal status) and complications of pregnancy and childbirth. Methods The hospital obstetric records, combined with follow-up survey. Data from 12 obstetrics and gynecology records of 12,224 primiparous women who were delivered between May 1992 and April 1993 in 8 hospitals in Beijing and records of follow-up surveys before discharge from the hospital. After lo-gistic regression analysis, we adjusted the pregnancy and reproductive outcomes by occupational category after adjusting for potential confounding factors such as age of pregnancy, smoking during pregnancy, alcohol consumption and history of spontaneous abortion. Results Among workers, the incidence of pregnancy-induced hypertension, low birth weight, intrauterine growth retardation and postpartum hemorrhage was significantly above average. Among the professional and technical personnel, threatened abortion, anemia of pregnancy, stillbirth and stillbirth, uterine contractions, overproduction of peasants, asphyxia of newborns, low birth weight in housewives, anemia of pregnancy among staff, weakening of contractions in management staff, etc. Rate, significantly higher than the average. Conclusion There is a certain relationship between occupational and non-pregnant pregnancies during pregnancy and reproductive outcomes.