Expression of DNA-dependent protein kinase in human granulocytes

• 作 者: AnnahitaSALLMYR AnnaMILLER Aid
• 机 构: DepartmentofMedicalMicrobiology,LaboratoryofNerveCellBiophysics
• 出 处: 细胞研究：英文版
• 发表日期: 2004年4期
• 关键词: 粒细胞 人类 蛋白激酶 基因修复 表达 非同源末端连接 多形核白细胞 DNA repair nonhomologous end-joining myeloi
• 基金项目: the Swedish Institute，Swedish Cancer Society, Malmo General Hospital Cancer Fund，Gustaf Vs 80arsfond Foundations

Human polymorphonuclear leukocytes (PMN) have been reported to completely lack of DNA-dependent protein kinase (DNA-PK) which is composed of Ku protein and the catalytic subunit DNA-PKcs, needed for nonhomologous end-joining (NHEJ) of DNA double-strand br