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目的对比分析左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的临床疗效。方法 55例消化性溃疡患者随机分为试验组(30例,左氧氟沙星三联疗法)与对照组(25例,阿莫西林三联疗法),比较两组疗效。结果试验组治疗总有效率为93.3%,对照组治疗总有效率为92.0%,两组患者的整体治疗效果比较,差异无统计学意义(P>0.05);试验组不良反应发生率为20.0%,对照组不良反应发生率为20.0%,两组不良反应发生率比较,差异无统计学意义(P>0.05);试验组患者平均治疗费用为(328.5±42.6)元,对照组为(411.6±52.1)元,试验组治疗费用明显低于对照组(t=6.51,P<0.05)。结论左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡均具有良好的临床疗效,且不良反应发生率无明显差异,而采用左氧氟沙星三联疗法治疗更能够减少治疗费用。
Objective To compare and analyze the clinical efficacy of levofloxacin triple therapy and amoxicillin triple therapy in the treatment of peptic ulcer. Methods 55 patients with peptic ulcer were randomly divided into experimental group (30 cases, levofloxacin triple therapy) and control group (25 cases, amoxicillin triple therapy). The curative effect was compared between the two groups. Results The total effective rate was 93.3% in the experimental group and 92.0% in the control group. There was no significant difference in the overall treatment effect between the two groups (P> 0.05). The incidence of adverse reactions in the experimental group was 20.0% The incidence of adverse reactions in the control group was 20.0%. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). The mean treatment cost was (328.5 ± 42.6) yuan in the experimental group and (411.6 ± 52.1) yuan, the treatment group was significantly lower than the control group (t = 6.51, P <0.05). Conclusion Levofloxacin triple therapy and amoxicillin triple therapy have a good clinical efficacy of peptic ulcer, and no significant difference in the incidence of adverse reactions, and levofloxacin triple therapy can reduce the cost of treatment.